COVORTS: Longitudinal Study of COVID-19 Smell Loss and Quality of Life

76 patients with persistent COVID-19-related smell loss were followed for one year with monthly questionnaires and quarterly home visits. The study, authored by S. Boesveldt and hosted by DANS Data Station Life Sciences, collected data on chemosensory dysfunction, eating behavior, and quality of life using tools like the Sniffin' Sticks test and the Olfactory Disorders Questionnaire. A second cohort, long COVORTS, aims to follow approximately 150 patients with long-term smell loss for another year.

Use Cases

• Modeling the progression of parosmia and phantosmia symptoms based on monthly self-reported olfactory perception.
• Analyzing the relationship between chemosensory dysfunction and eating behavior using Appetite, Hunger and Sensory Perception (AHSP) questionnaire scores.
• Predicting quality of life impact for long-COVID patients based on Olfactory Disorders Questionnaire (eODQ) responses.
• Correlating subjective self-reports with objective smell test results from the Sniffin' Sticks battery.

Strengths

• Longitudinal design with patient follow-up over one year.
• Combines subjective questionnaire data with objective clinical measurements like the Sniffin' Sticks test.
• Includes a specific cohort of 76 patients with PCR-confirmed SARS-CoV-2 infection and persistent smell loss.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the primary and secondary cohorts is unknown, which may limit suitability assessment.
• The SCENTinel test was added later, so not all patients completed it, creating potential data gaps.

Provenance

Source

S. Boesveldt, DANS Data Station Life Sciences Collection

Collection Method

Clinical cohort study involving online questionnaires and in-person home visits for testing.

Time Range

Study duration of one year per cohort; specific collection dates unknown.

Freshness

Last updated 2026-06-02 05:10:12; freshness should be verified.