Mechanochemical Synthesis Data for 2,3-Dihydrothiazoles and Thiazolidines

A 610.3 KB dataset on figshare details a solvent-free mechanochemical synthesis method. Vipin Kumar authored this dataset, which was last updated on June 4, 2026. The data likely contains reaction outcomes for synthesizing 2,3-dihydrothiazoles and thiazolidines from β-ketothioamides and α-bromoketones/1,3-dichloroprop-2-one.

Use Cases

• Train reaction prediction models based on the described substrate scope and functional group compatibility.
• Benchmark green chemistry metrics based on the solvent-free and energy-efficient mechanochemical process.
• Analyze chemo- and regioselectivity patterns based on the described substrate-controlled divergent synthesis.

Strengths

• Dataset is focused on a specific, solvent-free synthesis method with a reported reaction time of 15 minutes.
• The described process reportedly achieves higher yields compared to traditional solution-based methods.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Vipin Kumar via figshare

Collection Method

Likely contains experimental results from mechanochemical reactions conducted in a mortar and pestle.

Freshness

Last updated 2026-06-04 20:46:11; freshness should be verified.