STS-135: Mouse Retina Gene Expression Changes After Spaceflight

NASA's STS-135 mission hosted an animal experiment to study the molecular impact of spaceflight on retinal biology. Differential gene expression profiling was performed between mice flown in space and their ground control counterparts. The dataset likely contains results from histological, gene expression, and epigenetic analyses.

Use Cases

• Identify differentially expressed genes in retinal tissue based on spaceflight exposure.
• Analyze epigenetic changes in the mouse retina based on the experimental conditions.
• Compare molecular profiles between spaceflight and ground control cohorts.
• Model the impact of microgravity on mammalian ocular biology based on gene expression data.

Strengths

• Data originates from a controlled NASA spaceflight experiment on the STS-135 mission.
• Includes a ground control cohort for comparative analysis.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is provided in a BIN file format, which may require specialized tools for access.

Provenance

Source

National Aeronautics and Space Administration

Collection Method

Animal experiment conducted onboard the STS-135 space shuttle mission.

Freshness

Last updated 2026-03-13 19:24:51.431534; freshness should be verified