Iron(III) Complexes: Stereochemistry and Antitumor Activity

A 2026 figshare dataset by Astrid Dagmar Bernkop-Schnürch investigates chlorido iron(III) complexes. The dataset likely contains characterization and activity data for complexes differing in stereochemical configuration and halogen substituents. It focuses on the relationship between molecular structure and antitumor efficacy.

Use Cases

• Modeling antitumor activity based on stereochemical configuration described in the study.
• Analyzing the impact of halogen substituent patterns (Cl, Br) on biological activity.
• Investigating the role of oxidative stress and ferroptosis in the mode of action for specific complexes.
• Comparing the efficacy of (RS)-configured versus (RR/SS)- or (SS)-configured complexes.

Strengths

• All complexes were fully characterized, suggesting detailed chemical data.
• The dataset explicitly describes high stability with regard to ligand racemization.
• File size is 1011.0 B, indicating a compact, focused dataset.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset's scope is limited to a specific set of nine iron(III) complexes (1a–c, 2a–c, 3a–c).

Provenance

Source

figshare

Collection Method

Likely contains experimental characterization and biological assay data from a structure-activity relationship study.

Freshness

Last updated 2026-04-17 18:05:29.