<strong>Cerebrospinal fluid cytochemical analysis from COVID-19 patients with neurological

94 cerebrospinal fluid (CSF) samples from inpatients at Edgardo Rebagliati Martins Hospital in Peru, analyzed for physical, cytological, and chemical alterations. The study, authored by Eder Walttuoni-Picón, found the most frequent neurological disorders were encephalopathy (43%) and brain tumor (23%). It reports differences in protein concentration (p=0.001) between disorders but not in glucose concentration (p>0.05).

Use Cases

• Classifying neurological disorder types based on CSF physical characteristics like clarity and color mentioned in the description
• Predicting abnormal protein levels (>45 mg/dL) in CSF based on patient neurological conditions
• Analyzing relationships between leukocyte counts (<5 cells/ul) and specific disorders such as encephalopathy or brain tumor
• Comparing biochemical marker values (e.g., glucose, protein) across different neurological complications of COVID-19

Strengths

• Includes 94 CSF samples with associated patient diagnoses
• Reports specific statistical results, including p-values for protein concentration differences (p=0.001)
• Provides percentages for disorder prevalence (e.g., 43% encephalopathy) and biomarker abnormalities (e.g., 20% of encephalopathy patients had proteins >45mg/dl)

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect geographic bias inherent to a single hospital study in Peru

Provenance

Source

Eder Walttuoni-Picón via paperswithcode

Collection Method

Observational and cross-sectional study of CSF samples obtained by lumbar puncture

Geography

Peru (Edgardo Rebagliati Martins Hospital)