Structural Principles of Covalent Flavin Modification in Oxidoreductases

A review of structurally validated examples of covalent flavin inactivation in oxidoreductases, compiled by John J. Tanner and last updated in May 2026. The dataset likely contains information on enzyme families and structural outcomes derived from mining the Protein Data Bank. The file is 20.8 KB in size and is available in XLSX format.

Use Cases

• Analyzing structural outcomes of covalent flavin modification based on the review of X-ray crystallography data.
• Studying the prevalence of inactivation across enzyme families like monoamine oxidases and proline dehydrogenase as mentioned in the description.
• Investigating the chemical disposition of N5 or C4a alkylation events described in the structural record.

Strengths

• Data is derived from a review of structurally validated examples from the Protein Data Bank.
• The dataset is focused on a specific biochemical phenomenon: covalent flavin modification.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 20.8 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Likely compiled from a literature review and structural database mining.

Freshness

Last updated 2026-05-08 17:33:30; freshness should be verified.