Antibacterial Activity Data for 26 Cannabigerol Derivatives Against Gram-Positive Bacteria

Prashant S. Mandal's 2026 figshare dataset contains experimental results for 26 synthesized cannabigerol and cannabigerolic acid derivatives tested as antibacterial agents. It includes minimum inhibitory concentration (MIC) data against five Gram-positive bacterial strains, including MRSA and VRE. The data supports structure-activity relationship analysis for novel antibiotic discovery.

Use Cases

• Analyze the relationship between terpene chain lengths (6-13 carbons) and antibacterial activity across five bacterial strains.
• Compare minimum inhibitory concentrations (MICs) of CBG analogs to the reference drug daptomycin for potency benchmarking.
• Identify structural determinants for antibacterial potency by correlating substitution patterns with activity against Staphylococcus aureus and Enterococcus faecalis.

Strengths

• Data covers 26 distinct chemical derivatives, including 20 novel analogs.
• Results are validated against five clinically relevant Gram-positive bacterial strains, including MRSA and VRE.
• Includes critical potency metrics like minimum inhibitory concentrations (MICs).

Limitations

• Dataset is very small at 2.0 KB, indicating limited scope and sample size.
• Activity data is restricted to Gram-positive bacteria; no coverage of Gram-negative strains.
• No raw experimental data or column schema is provided, limiting analytical depth.

Provenance

Source

figshare, author Prashant S. Mandal.

Collection Method

Data from laboratory synthesis and characterization of 26 derivatives, followed by antibacterial activity testing.

Time Range

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Freshness

Last updated March 14, 2026.

Geography

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