Mammalian Mitochondrial Respiratory Supercomplex and ATP Synthase Cryo-EM Structures

Cryo-electron microscopy structures of mammalian mitochondrial respiratory supercomplexes (I, III, IV) and ATP synthase oligomers (FoF1, Fo). The dataset, uploaded by Ken Yokoyama, contains 26.3 GB of volumetric maps, atomic models, and validation reports for multiple conformational states. It was last updated on 2026-05-06.

Use Cases

• Modeling protein-protein interactions within the respiratory chain based on the supramolecular complex structures.
• Analyzing conformational changes in Complex I based on the provided closed and open form maps.
• Studying the oligomeric state and structure of ATP synthase using the FoF1 and Fo maps and models.
• Validating cryo-EM reconstruction quality using the provided half-maps and validation reports.

Strengths

• Contains 26.3 GB of high-resolution structural data, including multiple conformational states.
• Provides both volumetric cryo-EM maps (.mrc) and corresponding atomic coordinate files (.cif, .pdb) for direct analysis.
• Includes validation reports for each structure, which may support assessment of model quality.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, author Ken Yokoyama.

Collection Method

Analysis of cryo-electron microscopy images of submitochondrial particles (SMP).

Time Range

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Freshness

Last updated 2026-05-06 07:01:01; freshness should be verified.

Geography

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