ZYG11B-EloB-EloC Complex Cryo-EM Structures with Substrate Peptide

Cryo-EM structures of monomeric and dimeric ZYG11B-EloB-EloC complexes bound to a substrate peptide, deposited by Ni Lin on figshare. The dataset is 370.8 MB in size and was last updated on 2026-05-26. It contains PDB and MRC files detailing the assembly and functional mechanisms of the CRL2^ZYG11B ubiquitin ligase complex.

Use Cases

• Analyzing protein-protein interaction interfaces based on the described complex structures.
• Modeling ubiquitin ligase assembly mechanisms based on the monomeric and dimeric states.
• Validating computational docking predictions against the provided Cryo-EM structures.
• Studying substrate recognition by the CRL2^ZYG11B complex based on the bound peptide.

Strengths

• Dataset size is 370.8 MB, indicating substantial structural data.
• Includes both monomeric and dimeric states of the protein complex, providing comparative insights.
• Released under the permissive CC-BY-4.0 license for broad reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for certain analyses.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Cryo-electron microscopy (Cryo-EM) data collection and structure determination.

Freshness

Last updated 2026-05-26 07:03:31; freshness should be verified.