STS-135: Mouse Liver Metabolomics from Spaceflight

Mice were flown onboard the STS-135 space shuttle mission and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen before being analyzed by Metabolon, Inc. The dataset is provided by the National Aeronautics and Space Administration and was last updated in March 2026.

Use Cases

• Identify metabolic pathway disruptions based on liver tissue analysis from spaceflight.
• Compare spaceflight-induced metabolic changes to terrestrial control models.
• Investigate the acute physiological response to re-entry and landing based on samples collected within hours.
• Correlate metabolomic profiles with other space biology datasets from the same mission.

Strengths

• Samples were collected under controlled conditions within 3-4 hours of landing from the STS-135 mission.
• Analysis was performed by a specialized commercial entity, Metabolon, Inc.
• Dataset originates from the authoritative source, the National Aeronautics and Space Administration.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count and dataset scale are unknown, which may limit suitability assessment.
• Data is stored in a BIN format, which may require specific tools for access and interpretation.

Provenance

Source

National Aeronautics and Space Administration

Collection Method

Mice were flown on the STS-135 space shuttle, livers were collected post-landing and analyzed by Metabolon, Inc.

Freshness

Last updated 2026-03-13 19:27:11.870554; freshness should be verified.