HLA Genetic Study Summary Statistics for SSc-ILD Comparisons

Summary statistics from a genetic study comparing HLA profiles across three groups: patients with systemic sclerosis and interstitial lung disease (SSc-ILD+), patients with systemic sclerosis without ILD (SSc-ILD-), and controls. The dataset, authored by Carlos Rosa-Baez and last updated in May 2026, is a 7.1 MB TSV file containing the results of these three primary comparisons.

Use Cases

• Identify genetic associations with interstitial lung disease in systemic sclerosis based on HLA summary statistics.
• Compare allele frequencies between SSc patients with and without lung disease based on the SSc-ILD+ vs SSc-ILD- comparison.
• Assess genetic risk factors by comparing patient groups to healthy controls using the provided summary statistics.

Strengths

• Dataset is 7.1 MB, indicating a manageable size for analysis.
• Data is licensed under CC-BY-4.0, permitting broad reuse with attribution.
• Specific comparisons (SSc-ILD+ vs SSc-ILD-, etc.) are clearly defined in the description.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Carlos Rosa-Baez via figshare

Collection Method

Likely derived from a genetic association study, but specific methodology is not detailed.

Freshness

Last updated 2026-05-26 10:52:40; freshness should be verified.