50 dlPFC samples from control and MDD groups were analyzed using the Agilent Human 8 x 15K SuperEnhancer-LncRNA expression array. The dataset was created by Bhaskar Roy and last updated on 2026-05-18. Quantile normalization and data processing were performed using the GeneSpring GX v12.1 software package.
Use Cases
- Identify differentially expressed super-enhancer-associated lncRNAs based on the microarray expression data.
- Investigate potential biomarkers for Major Depressive Disorder based on gene expression profiles from dlPFC tissue.
- Perform co-expression network analysis to explore regulatory relationships between lncRNAs and nearby genes.
- Validate findings from other genomic studies of depression using this specific expression array platform.
Strengths
- Includes 50 samples from control and MDD groups, providing a basis for comparative analysis.
- Data was processed using standardized microarray protocols and quantile normalization via GeneSpring GX v12.1 software.
- Focuses on super-enhancer-associated lncRNAs, a specific and functionally relevant genomic feature.
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
- Data may reflect bias inherent to the specific brain region (dlPFC) and sample collection methodology.
Provenance
- Source
- figshare, author Bhaskar Roy
- Collection Method
- Microarray analysis of total RNA from dlPFC samples using the Agilent Human 8 x 15K SuperEnhancer-LncRNA expression array.
- Freshness
- Last updated 2026-05-18 15:57:11; freshness should be verified.