Supplementary data: Antiretroviral therapy persistence among treatment-experienced people

Supplementary data for a retrospective cohort study analyzing antiretroviral therapy persistence among 14,826 treatment-experienced people with HIV in the USA. The data includes 5,310 individuals with a mental health disorder and/or substance use disorder and 409 with suboptimal adherence. The dataset was created by Uche Mordi and published on figshare in 2026.

Use Cases

• Compare treatment persistence across different antiretroviral regimens based on claims data analysis.
• Assess the impact of mental health and substance use disorders on HIV therapy adherence.
• Evaluate the effectiveness of inverse probability treatment weighting for balancing cohort characteristics.
• Model time-to-discontinuation or switch using Kaplan–Meier and Cox proportional hazards methods.

Strengths

• Data covers a 7-year period from 2017 to 2024.
• Study population includes 14,826 treatment-experienced people with HIV.
• Analysis includes specific subgroups: 5,310 with MHD/SUD and 409 with PDC <85%.

Limitations

• Row count for the supplementary tables is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is limited to a single claims database (Optum Research Database), which may reflect source-specific biases.

Provenance

Source

Optum Research Database (claims data).

Collection Method

Retrospective cohort study using claims data, with baseline characteristics balanced by inverse probability treatment weighting.

Time Range

2017-07-01 to 2023-11-30 (study period), with data covering up to 2024.

Freshness

Last updated 2026-04-23 15:12:32; freshness should be verified.

Geography

United States.