Longitudinal Study on Faecal Urease Activity and Nappy Rash Incidence in Six Infants

A longitudinal observational study conducted at the Westwood Nursery, University of Bath, investigated the correlation between urease activity in infant faeces and nappy rash incidence. The study analyzed soiled nappies donated up to twice weekly from six infants over a 9-month period. Results demonstrated a clear statistical correlation between urease expression and observed rash incidence.

Use Cases

• Analyze correlation between faecal enzyme activity and skin health based on longitudinal observations
• Study the role of urease-expressing bacteria in diaper dermatitis pathogenesis based on the described causal chain
• Validate statistical methods for small-sample longitudinal studies in infant health based on chi-squared analysis results

Strengths

• Dataset includes longitudinal data collected over 9 months
• Statistical analysis shows a significant correlation (P < 0.0002)
• Data collection involved both biochemical analysis of faecal samples and clinical skin condition recording

Limitations

• Dataset size is very small (914.4 KB), suggesting limited scope
• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download

Provenance

Source

Krystal A. Le Doaré via figshare

Collection Method

Longitudinal observational study with analysis of soiled nappies and skin condition recording by nursery staff

Time Range

Study conducted over 9 months

Freshness

Last updated 2026-05-25 06:03:23; freshness should be verified

Geography

Westwood Nursery, University of Bath, United Kingdom