One Health Analysis of Antibiotic Resistance Reports in Global Pharmacovigilance Databases

29,667 human and 5,217 animal adverse event reports related to potential antibiotic resistance were identified in VigiBase and EudraVigilance Veterinary databases up to February 21, 2024. The dataset was created by Joseph Mitchell and published on figshare under a CC-BY-4.0 license. It represents a cross-sectional analysis exploring the 'One Health' framework across human, animal, and environmental domains.

Use Cases

• Analyze temporal trends in antibiotic resistance reports based on the mention of increasing reports over time.
• Compare human and animal antibiotic resistance signals based on data from VigiBase and EudraVigilance Veterinary.
• Assess global reporting patterns for antibiotic resistance based on the description of reports received from across the globe.
• Investigate the scarcity of environment-related antibiotic resistance reports based on the finding of only 52 environment-related reports, none concerning resistance.

Strengths

• Includes 29,667 human adverse event reports from VigiBase.
• Includes 5,217 animal adverse event reports from EudraVigilance Veterinary.
• Data covers reports received globally up to February 21, 2024.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the combined dataset is unknown, which may limit suitability assessment.
• The description notes a scarcity of environment-related reports and a lack of a dedicated global database for animal and environmental pharmacovigilance.

Provenance

Source

VigiBase (WHO) and EudraVigilance Veterinary (European Medicines Agency).

Collection Method

Searches performed on all reports received up to February 21, 2024.

Time Range

Reports up to February 21, 2024.

Freshness

Last updated 2026-05-28 06:17:11; freshness should be verified.

Geography

Global.