Meta-Analysis Data on Periodontitis, Tooth Loss, and Mild Cognitive Impairment Risk

Congcong Zou's supplementary file from a 2026 meta-analysis investigates the association between periodontitis, tooth loss, and mild cognitive impairment (MCI). The 519.8 KB document contains the full analysis, including pooled odds ratios, confidence intervals, and results from subgroup and sensitivity analyses. The work is licensed under CC-BY-4.0 and was last updated on March 18, 2026.

Use Cases

• Replicating the meta-analysis results based on the reported odds ratios and confidence intervals.
• Conducting secondary analyses on subgroups like severe periodontitis or significant tooth loss.
• Reviewing methodological approaches for systematic reviews in medical literature.
• Synthesizing evidence on oral health as a potential risk factor for cognitive impairment.

Strengths

• Includes fully-adjusted odds ratios (aORs) with 95% confidence intervals for primary associations.
• Reports results from subgroup analyses using specific diagnostic criteria (CDC-AAP).
• Conducted sensitivity analysis to confirm the robustness of the findings.
• Document is under a permissive CC-BY-4.0 license for reuse.

Limitations

• The dataset is a 519.8 KB DOCX file, indicating a limited scope as a supplementary document rather than raw study data.
• Row count and column-level documentation are absent; data structure must be inferred from the text.
• The description does not specify the number of individual patient records or source studies beyond the five included in the main meta-analysis.

Provenance

Source

figshare, author Congcong Zou.

Collection Method

Systematic review and meta-analysis of studies from PubMed, Embase, Web of Science, Cochrane Library, and MEDLINE up to March 2025.

Time Range

Literature search covered studies up to March 2025.

Freshness

Last updated 2026-03-18 06:57:55.