Supplementary file 1_Anti–interferon-γ autoantibody–associated adult-onset immunodeficienc

A case report from Wenzhou, China, details a 59-year-old male patient with adult-onset immunodeficiency associated with anti-interferon-γ autoantibodies. The report describes sequential severe infections by Salmonella enteritidis, Legionella pneumophila, and Talaromyces marneffei over one year, along with the patient's treatment and recovery. Authored by Xiran Zhou and published on figshare under CC-BY-4.0 license, the document was last updated on May 13, 2026.

Use Cases

• Study the clinical presentation and progression of anti-interferon-γ autoantibody-associated immunodeficiency based on the detailed case description.
• Analyze treatment efficacy for sequential intracellular infections based on the described regimen of rituximab and antimicrobial therapy.
• Investigate diagnostic challenges for immunodeficiencies with unremarkable immunophenotypes based on the case's 'silent disruptor' nature.

Strengths

• Provides a detailed clinical narrative of a rare immunodeficiency syndrome.
• Includes specific patient demographics (59-year-old male from Wenzhou, China) and a timeline of infections over one year.
• Describes a specific treatment protocol involving rituximab and targeted antimicrobial therapy.

Limitations

• Data is presented as a single case report (DOCX file), limiting statistical generalizability.
• Row count and column-level data are unknown, restricting quantitative analysis.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Clinical case documentation.

Time Range

Covers a one-year period of patient illness and treatment.

Freshness

Last updated 2026-05-13 05:55:20; freshness should be verified.

Geography

Wenzhou, Zhejiang Province, China.