Artemisia scoparia Extract Effects on MASH Mouse Model

18.1 KB supplementary document details a study on Artemisia scoparia extract for metabolic dysfunction-associated steatohepatitis (MASH). Linlin Wang authored this CC-BY-4.0 licensed file, uploaded to figshare on April 15, 2026. The research combines transcriptomic and metabolomic analyses to identify 30 dysregulated genes and 60 metabolic metabolites affected by the treatment.

Use Cases

• Identifying dysregulated genes in MASH based on transcriptomic data mentioned in the description
• Analyzing metabolic pathway alterations based on the 60 metabolites listed in the results
• Studying AGE-RAGE and JAK-STAT signaling pathway inhibition based on the described mechanisms
• Comparing in vivo and in vitro hepatoprotective effects based on the described experimental methods

Strengths

• The study integrates transcriptomic and metabolomic analyses, providing a multi-omics perspective
• Results identify specific dysregulated genes (e.g., Gm15622, Pdia6, Derl3) and metabolites (e.g., heptadecanoic acid)
• The dataset is openly licensed under CC-BY-4.0

Limitations

• The dataset is a 18.1 KB supplementary document, indicating limited raw data scope
• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Data likely generated from in vivo and in vitro experiments on a MASH mouse model and HepG2 cells, analyzed via transcriptomics, metabolomics, Western blotting, and immunofluorescence staining.

Freshness

Last updated 2026-04-15 05:45:41