Global and Local Atrial Fibrillation Risk Factors in Young Adults, 1990-2021

Supplementary file 1 from a hybrid study by Ye Liu assesses modifiable risk factors for atrial fibrillation and flutter in young adults aged 15-39 years. The dataset likely contains results from a global burden analysis spanning 1990 to 2021 and a local cohort study, including age-standardized rates and regression analyses. It was last updated on figshare in May 2026 under a CC-BY-4.0 license.

Use Cases

• Modeling the association between hypertension and atrial arrhythmia risk based on the identified key modifiable factor.
• Projecting future disease burden among young adults using the Bayesian age-period-cohort (BAPC) analysis results.
• Analyzing non-linear relationships between diastolic blood pressure (DBP) and BMI with atrial arrhythmia using restricted cubic splines.
• Comparing atrial fibrillation burden across Socio-demographic Index (SDI) areas based on global prevalence, incidence, and DALY rates.

Strengths

• Includes a 31-year global time series (1990-2021) for longitudinal analysis.
• Identifies specific risk factor thresholds, such as a DBP breakpoint at 88.3 mmHg and a BMI breakpoint at 28.8 kg/m².
• Integrates population-level global data with individual-level cohort study results for a hybrid analysis.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The 50.1 MB file size suggests a relatively small dataset, potentially limiting statistical power for some analyses.

Provenance

Source

Ye Liu via figshare.

Collection Method

Hybrid study integrating global data analysis (likely from GBD) with a local cohort study using multivariable logistic regression.

Time Range

1990 to 2021 for global analysis; cohort study time range is unspecified.

Freshness

Last updated 2026-05-29 04:46:48; freshness should be verified.

Geography

Global analysis by regions; local cohort geography is unspecified.