Tadpole Gut Microbiota Response to ZnO Nanoparticles and Glyphosate

figshare document analyzes the individual and combined effects of zinc oxide nanoparticles and glyphosate on the gut microbiota of Rana dybowskii tadpoles. The study uses 16S rRNA sequencing, diversity indices, and functional pathway predictions to assess pollutant-induced dysbiosis. Data includes microbial community shifts, dysbiosis index scores, and ecological assembly models.

Use Cases

• Analyze shifts in dominant phyla like Firmicutes, Proteobacteria, and Actinobacteriota across pollutant exposure treatments.
• Model ecological assembly processes using the dataset's community assembly models to understand deterministic vs. stochastic drivers of microbiota change.
• Correlate gut microbiota dysbiosis index (MDI) values with specific pollutant treatments to quantify microbial imbalance.
• Predict functional pathway disruptions using the referenced Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis results.

Strengths

• Study integrates multiple analytical approaches: alpha and beta diversity indices, a dysbiosis index (MDI), and ecological assembly models.
• Focuses on a relevant environmental health issue: co-contamination effects on amphibian microbiota.
• Data is derived from controlled experimental treatments (control, ZnO NPs, glyphosate, and combined exposure).

Limitations

• Dataset is a 5.0 MB DOCX file, not a structured table, requiring manual extraction of numerical results for analysis.
• Sample size (number of tadpoles or sequencing samples) is not specified in the provided input.
• Data is specific to Rana dybowskii tadpoles, limiting direct applicability to other species or life stages.

Provenance

Source

Han Xue-dong via figshare.

Collection Method

Experimental exposure study with 16S rRNA gene (V3-V4 region) sequencing on an Illumina MiSeq platform.

Time Range

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Freshness

Last updated March 2026.

Geography

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