Stress Hyperglycaemia Ratio and Diabetic Retinopathy Association in 1,924 T2DM Patients

A retrospective cross-sectional study of 1,924 inpatients with type 2 diabetes mellitus (T2DM) investigates the association between glycaemic control indices and diabetic retinopathy (DR). The study, authored by Deyuan Zhang and last updated in May 2026, employs multivariate logistic regression and mediation analysis to examine stress hyperglycaemia ratio (SHR), FBG/HbA1c, and P2hBG/HbA1c, exploring mediating effects of lipid ratios.

Use Cases

• Modeling the association between stress hyperglycaemia ratio (SHR) and diabetic retinopathy risk based on patient cohort data.
• Investigating the mediating role of lipid ratios (NHHR, TG/HDL-C) in glycaemic marker and disease outcome relationships.
• Validating linear associations across patient subgroups using restricted cubic spline (RCS) analysis as described.
• Training predictive models for diabetic retinopathy using derived glycaemic indices from clinical measurements.

Strengths

• Includes data from 1,924 T2DM patient records, providing a substantive cohort for analysis.
• Analyzes multiple specific glycaemic indices (SHR, FBG/HbA1c, P2hBG/HbA1c) and their associations with detailed statistical results (ORs, CIs) provided.
• Employs advanced statistical methods including mediation analysis, subgroup analysis, and restricted cubic spline modeling.

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment.
• Data is from a single-center inpatient study, which may reflect specific institutional or geographic biases.
• The dataset is very small (23.1 KB), indicating limited scope, likely containing summary results or a minimal subset of the full study data.

Provenance

Source

figshare, authored by Deyuan Zhang.

Collection Method

Retrospective cross-sectional study based on inpatient records at a single center.

Time Range

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Freshness

Last updated 2026-05 05:40:42; freshness should be verified.

Geography

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