Meta-Analysis Data on Frailty and Depression in Older Adults with Coronary Heart Disease

Supplementary data from a systematic review and meta-analysis investigating the association between frailty and depression in older adults with coronary heart disease. The analysis includes 6 studies comprising 2,628 patients, with a pooled odds ratio of 2.45. The document was authored by Yuan Chen and last updated in April 2026.

Use Cases

• Conducting secondary analysis of the pooled odds ratio (OR=2.45) and confidence intervals for the frailty-depression association.
• Examining heterogeneity (I²=90%) and subgroup results by study design (cohort vs. cross-sectional).
• Reviewing the systematic review methodology, including database searches from inception to April 2025 and quality assessment tools.
• Identifying gaps in the evidence base, such as the need for prospective studies, as highlighted in the conclusion.

Strengths

• Includes a specific pooled odds ratio (OR=2.45) with 95% confidence intervals (1.22–4.92).
• Reports on 2,628 patients from 6 included studies, providing a quantifiable sample size.
• Documents the systematic review protocol registration (PROSPERO CRD420251036929).
• Provides subgroup analysis results by study design (cohort OR=3.92, cross-sectional OR=1.91).

Limitations

• The dataset is a single 18.8 KB DOCX file; the underlying study-level data is not provided in a structured, machine-readable format.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for computational analysis.

Provenance

Source

Yuan Chen, via figshare.

Collection Method

Systematic review and meta-analysis of observational studies from PubMed, Embase, and Web of Science.

Time Range

Literature search from database inception to April 2025.

Freshness

Last updated 2026-04-13 04:30:41.

Geography

Studies included are not geographically specified; the patient population is older adults with coronary heart disease.