Naples Prognostic Score and Parkinson Disease Risk in UK Biobank Participants

Zhiqiang Xu's supplementary file contains data from a prospective cohort study of 317,035 UK Biobank participants recruited between 2006 and 2010. The study analyzes the association between the Naples prognostic score, derived from inflammatory and nutritional biomarkers, and incident Parkinson disease risk over a median follow-up of 13.94 years. The file was last updated on April 30, 2026.

Use Cases

• Modeling Parkinson disease risk based on the Naples prognostic score and its component biomarkers.
• Analyzing dose-response relationships between systemic immune-metabolic status and neurodegenerative outcomes.
• Validating the Naples prognostic score as a risk stratification tool for Parkinson disease in a large prospective cohort.

Strengths

• Data is derived from a large cohort of 317,035 UK Biobank participants.
• Study features a long median follow-up period of 13.94 years.
• Analysis uses a validated algorithm for Parkinson disease identification.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is a single 81.5 KB DOCX file, indicating a very limited data scope.

Provenance

Source

UK Biobank

Collection Method

Prospective cohort study with data collected from 2006-2010 and follow-up through December 2022.

Time Range

Baseline recruitment 2006-2010, follow-up through 2022.

Freshness

Last updated 2026-04-30 05:38:44; freshness should be verified.

Geography

United Kingdom (UK Biobank participants).