Associations of Diabetes, Retinopathy, and Cognitive Outcomes in Older Adults

A multi-dataset observational study from the National Health and Nutrition Examination Survey, UK Biobank, and the Wenzhou dataset examines links between diabetes mellitus, diabetic retinopathy, and cognitive outcomes. The study, authored by Guiqian Huang and last updated in May 2026, includes dietary inflammatory index scores derived from dietary recalls. It uses weighted multivariable-adjusted Poisson regression, robust Cox proportional hazards regression, and conditional logistic regression across the datasets.

Use Cases

• Analyze associations between diabetes mellitus and cognitive performance based on cognitive test scores.
• Investigate the mediating role of the dietary inflammatory index in the link between diabetic retinopathy and cognitive impairment.
• Compare cognitive outcome associations across different population datasets (NHANES, UK Biobank, Wenzhou).

Strengths

• Multi-source data from three distinct observational datasets (NHANES, UK Biobank, Wenzhou).
• Applies multiple statistical models (Poisson regression, Cox regression, logistic regression) tailored to each dataset.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

National Health and Nutrition Examination Survey (NHANES), UK Biobank, Wenzhou dataset.

Collection Method

Observational study using dietary recalls and cognitive assessments.

Freshness

Last updated 2026-05-12 04:19:04; freshness should be verified.

Geography

United States (NHANES), United Kingdom (UK Biobank), Wenzhou, China.