Supplementary File 1: Baicalein Effects on Gouty Arthritis in Mice

A supplementary PDF file from a study investigating the therapeutic effects of baicalein on gouty arthritis. The research involved in vivo experiments with 30 BALB/c male mice and in vitro experiments with RAW264.7 macrophages, measuring behavioral scores, cytokine levels, and cell polarization. The file, authored by Mingli Han, was last updated on 2026-04-23.

Use Cases

• Analyzing the dose-dependent effects of baicalein on joint swelling and inflammatory infiltration based on the described mouse model experiments.
• Studying the molecular mechanism of baicalein on NF-κB signaling and cytokine secretion based on the described in vitro assays.
• Investigating the relationship between macrophage M2 polarization and synovial inflammation reduction based on the described CD206 and IL-10 marker analysis.

Strengths

• The dataset is associated with a structured experimental design involving 30 mice across 5 treatment groups.
• The study employs multiple validation methods, including behavioral scoring, histopathology, RT-qPCR, and Western blotting.

Limitations

• The dataset is a 126.4 KB PDF file; the underlying raw experimental data is not directly accessible in a structured, machine-readable format.
• Column-level documentation is absent; field semantics must be inferred from the PDF text after download.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.

Provenance

Source

figshare

Collection Method

Data likely originates from laboratory experiments described in the associated research study.

Time Range

The temporal coverage of the experimental data is not specified.

Freshness

Last updated 2026-04-23 04:21:37; freshness should be verified.

Geography

The spatial coverage of the data is not specified.