CircRNA Expression and Clinical Indicators in Rheumatoid Arthritis Patients

582.8 KB supplementary data from a study investigating circ_0000734 expression in rheumatoid arthritis. The data likely contains expression levels of circ_0000734 in peripheral blood mononuclear cells from RA patients and their correlation with clinical indicators like RF, anti-CCP, CRP, ESR, and DAS28 scores. Yanqiu Sun published the data on figshare under a CC-BY-4.0 license in 2026.

Use Cases

• Analyze correlations between circRNA expression and disease activity scores based on clinical indicators mentioned in the description
• Investigate the regulatory relationship between circRNAs and inflammatory pathways based on NF-κB signaling pathway data
• Validate bioinformatics predictions of miRNA targets based on dual-luciferase reporter assay results
• Assess the effects of a natural compound on inflammatory cytokine profiles based on IL-17, IL-23, IL-4, and IL-10 expression data

Strengths

• 582.8 KB file size suggests a focused dataset with specific molecular and clinical measurements
• Data is associated with a detailed experimental methodology including qRT-PCR, flow cytometry, and ELISA

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download

Provenance

Source

figshare

Collection Method

Likely generated from laboratory experiments including qRT-PCR, dual-luciferase reporter assays, and cell culture models.

Freshness

Last updated 2026-05-28 04:50:48; freshness should be verified