Environmental E. coli Strains with Colistin Resistance and Oxidant Tolerance

Several E. coli strains isolated from mixed wastewater show colistin resistance with IC50 values ranging from 6.5 to 27.3 μg/ml. The dataset, authored by Asmaa Al-Mesaifri and last updated in June 2026, includes whole genome sequencing data and phenotypic characterization of strains resistant to multiple antibiotics and DNA-damaging agents. It is shared under a CC-BY-4.0 license as a 5.8 MB DOCX file on figshare.

Use Cases

• Identify genetic mutations linked to oxidant tolerance based on whole genome sequencing data mentioned in the description.
• Analyze the correlation between mcr-1 gene presence and colistin resistance levels based on the reported IC50 values.
• Study cross-resistance patterns to antibiotics like ciprofloxacin and tetracycline in environmental isolates.
• Investigate DNA repair mechanisms in bacteria resistant to hydrogen peroxide and ultraviolet radiation.

Strengths

• Includes specific quantitative resistance data (IC50 values ranging from 6.5 to 27.3 μg/ml).
• Contains whole genome sequencing data for genetic analysis.
• Phenotypic data covers resistance to multiple antibiotic classes and DNA-damaging agents.

Limitations

• Data is provided as a single DOCX document; column-level structure and row count are unknown.
• The dataset's 5.8 MB size suggests it is relatively small in scale.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

E. coli strains were isolated from mixed wastewater and characterized biochemically and genomically.

Freshness

Last updated 2026-06-02 22:02:19; freshness should be verified.