Broad-Spectrum Phage Cocktail Efficacy Against Campylobacter in Galleria mellonella

A supplementary research document details the in vitro and in vivo testing of a four-phage cocktail targeting Campylobacter jejuni and Campylobacter coli. The study, authored by Estibaliz Ruiz-Santamaría and last updated in April 2026, reports on the phage cocktail's lytic spectrum against 13 strains and its efficacy in improving larval survival in a Galleria mellonella model.

Use Cases

• Evaluating phage cocktail efficacy based on in vitro lysis results against 13 Campylobacter strains.
• Assessing strain-dependent virulence in an intermediate host model based on Galleria mellonella larval survival data.
• Optimizing phage-antibiotic combination therapy based on survival rates with erythromycin or ciprofloxacin.

Strengths

• The study provides specific quantitative results, including larval survival increasing from 25.5% to 57.5% with phage treatment.
• Data includes testing against 13 distinct Campylobacter strains, suggesting a broad assessment.
• Results are published under a CC-BY-4.0 license, permitting open reuse.

Limitations

• The dataset is a 196.9 KB DOCX file, which is a small supplementary document rather than a primary data repository.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.

Provenance

Source

figshare

Collection Method

Experimental research data from in vitro assays and in vivo Galleria mellonella model trials.

Time Range

The study period is not specified, but the file was updated in April 2026.

Freshness

Last updated 2026-04-15 05:44:12; freshness should be verified.

Geography

Spatial coverage is not specified.