Mouse Model Data on Caffeine Attenuation of Cisplatin-Induced Cognitive Dysfunction

A figshare document authored by Alfredo Oliveros, last updated in May 2026, details research on chemotherapy-induced cognitive impairments. The 3.5 MB file presents findings from a mouse model study investigating the role of adenosine A2A receptors and the neuroprotective effects of caffeine against cisplatin-induced neurotoxicity.

Use Cases

• Analyze the relationship between adenosine A2A receptor levels and chemotherapy-induced cognitive impairment based on the described mouse model.
• Investigate the morphological changes in microglia associated with cisplatin treatment as described in the research.
• Study the potential neuroprotective effects of caffeine on dendritic spine density and neurogenesis as outlined in the document.
• Model the physical recovery and motor function outcomes following caffeine intervention in cisplatin-treated mice.

Strengths

• The dataset is openly licensed under CC-BY-4.0.
• The document is a detailed research supplement focusing on a specific neurobiological mechanism.

Limitations

• The primary data format is a 3.5 MB DOCX file, which may require conversion for programmatic analysis.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Likely generated from laboratory experiments on mouse models as described.

Freshness

Last updated 2026-05-13 05:35:54; freshness should be verified.