Calibrated Abdominal Compression Data for Fluid Responsiveness in Preterm Neonates

A prospective, single-center pilot study conducted in a tertiary neonatal intensive care unit analyzed 18 fluid boluses in mechanically-ventilated preterm neonates under 32 weeks gestational age. Stroke volume was measured by echocardiography at baseline, during abdominal compression, and after fluid bolus, with fluid-responsiveness defined as a ≥15% increase. The study was authored by Julien Gotchac and published on figshare in April 2026.

Use Cases

• Predicting fluid-responsiveness based on stroke volume changes induced by abdominal compression.
• Evaluating the feasibility and tolerance of a calibrated abdominal compression maneuver in preterm neonates.
• Calculating diagnostic accuracy metrics like AUROC, specificity, and sensitivity for a ΔSV-AC threshold.
• Analyzing adverse event rates associated with a preload challenge in a neonatal ICU population.

Strengths

• All 18 cases included echocardiographic measurements at three time points: baseline, during compression, and post-bolus.
• Provides specific performance metrics: AUROC of 0.76 and a best ΔSV-AC threshold of 17% with specificity of 0.91.
• Includes detailed safety observations, noting three cases of transient adverse events.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is from a single-center pilot study with 18 boluses, limiting generalizability.

Provenance

Source

figshare

Collection Method

Prospective clinical pilot study with echocardiographic measurements.

Freshness

Last updated 2026-04-09 05:19:59; freshness should be verified.

Geography

Single tertiary neonatal intensive care unit (location unknown).