Cannabinoid Receptor Expression in SLE Patient Lymphocytes, 70 Samples

A study profiling cannabinoid receptor expression in lymphocyte subsets from 35 systemic lupus erythematosus patients and 35 healthy controls. The data was generated using multiparametric flow cytometry and reveals associations between receptor expression and disease activity. The dataset was authored by Angie M. Rosero and last updated on 2026-06-03.

Use Cases

• Identifying immune cell biomarkers for SLE disease activity based on CB1R and CB2R expression levels.
• Comparing lymphocyte subset profiles between SLE patients and healthy controls.
• Evaluating the potential of cannabinoid receptor modulation as a therapeutic target for autoimmune conditions.
• Training classifiers to distinguish between active disease and remission states using receptor distribution patterns.

Strengths

• Includes data from 70 total samples (35 SLE patients and 35 healthy controls).
• Employs multiparametric flow cytometry, a high-resolution technique for cell profiling.
• Results show statistically significant correlations with clinical disease activity.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is relatively small at 2.9 MB.

Provenance

Source

figshare

Collection Method

Multiparametric flow cytometry analysis of peripheral blood mononuclear cells.

Freshness

Last updated 2026-06-03 06:08:28; freshness should be verified.