CTRP9 and Vascular Calcification Biomarker Study in Coronary Heart Disease Patients

A cross-sectional observational study of 900 coronary heart disease patients evaluated the association of circulating CTRP9 with aortic valve and coronary artery calcification. Serum CTRP9 was measured in a subset, and logistic regression identified determinants of coronary artery calcification. The dataset includes results from ROC analysis and a supporting mouse model experiment.

Use Cases

• Predicting coronary artery calcification severity based on CTRP9 biomarker levels.
• Evaluating the combined predictive power of CTRP9 and aortic valve calcification for severe coronary artery calcification.
• Investigating the protective role of CTRP9 against vascular calcification in a mouse model.

Strengths

• Includes results from a study of 900 coronary heart disease patients.
• Provides specific statistical metrics (OR=0.156, AUC=0.74, AUC=0.843) for biomarker associations.
• Combines human clinical data with a supporting mouse model experiment.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small (35.6 KB), suggesting limited scope.

Provenance

Source

figshare, authored by Yanru Duan.

Collection Method

Cross-sectional observational study using echocardiography, optical coherence tomography, and serum measurements.

Freshness

Last updated 2026-04-29 05:40:55; freshness should be verified.