Clinical Outcomes of Preimplantation Genetic Testing for Chromosomal Inversions, 2019-2024

A retrospective analysis of couples undergoing preimplantation genetic testing (PGT) between January 2019 and December 2024. The dataset, authored by Yutong Li and shared under a CC-BY-4.0 license, compares euploid and aneuploid blastocyst rates across groups defined by chromosomal inversion, polymorphic variation, normal karyotype, and other balanced rearrangements.

Use Cases

• Compare euploid blastocyst rates between groups with chromosomal inversions, polymorphic variations, and normal karyotypes based on the study's subgroup analysis.
• Analyze the influence of carrier gender on aneuploidy rates in chromosomal inversion cases based on the reported significant difference.
• Investigate the relationship between inverted fragment size and aneuploid blastocyst proportion based on the described linear trend.
• Evaluate the clinical significance of pericentric versus paracentric inversion types based on the reported difference in aneuploidy rates.

Strengths

• Clear temporal coverage from January 2019 to December 2024.
• Study reports specific, statistically significant findings (e.g., 38.94% aneuploid rate for pericentric vs. 23.60% for paracentric inversions).
• Data is shared under a permissive CC-BY-4.0 license.

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment.
• The dataset is a 56.0 KB PDF file, suggesting limited scope or summary-level data rather than raw records.
• Description metadata is limited; actual data quality and structure require manual inspection after download.

Provenance

Source

figshare

Collection Method

Retrospective clinical study.

Time Range

January 2019 to December 2024

Freshness

Last updated 2026-04-24 09:13:34.

Geography

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