Cognitive and Affective Theory of Mind in Parkinson's Disease Pre- and Post-DBS

27 Parkinson's disease patients were assessed before and one year after bilateral subthalamic nucleus deep brain stimulation surgery. The dataset includes results from the Yoni Theory of Mind paradigm, the Montreal Cognitive Assessment, and a tablet-based neurocognitive test battery. It was collected at Charité Universitätsmedizin Berlin between June 2019 and September 2021.

Use Cases

• Analyze correlations between Yoni Theory of Mind task performance and Montreal Cognitive Assessment scores across 27 patients.
• Assess changes in neuropsychological domains like reaction time and visual learning from pre- to post-DBS surgery using CANTAB Connect test results.
• Investigate the association between disease duration and specific cognitive deficits in Parkinson's disease patients undergoing DBS.

Strengths

• Longitudinal design with pre- and post-operative assessments for 27 patients.
• Includes multi-modal cognitive data from the Yoni paradigm, MoCA, and CANTAB Connect neuropsychological tests.
• Patient cohort is well-characterized with specific demographics: average age of 58.7 years and average disease duration of 10.2 years.

Limitations

• Small sample size of 27 patients limits statistical power and generalizability of findings.
• Data is presented in a PDF report (575.3 KB), not in a structured, machine-readable tabular format.
• Geographic scope is limited to a single medical center in Berlin, Germany.

Provenance

Source

Anna Elsenbach via figshare.

Collection Method

Prospective clinical study applying the Yoni ToM paradigm, MoCA, and CANTAB Connect tests before and after DBS surgery.

Time Range

Data collected between June 2019 and September 2021, with a one-year follow-up.

Freshness

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Geography

Charité Universitätsmedizin Berlin, Germany.