Colistin Use and Clinical Outcomes in Kuwait Public Hospitals, 205 Patients

A retrospective observational study of 205 patients treated with colistin across five hospitals in Kuwait. The dataset likely contains patient-level data on dosing regimens, clinical cure rates, incidence of nephrotoxicity and neurotoxicity, and mortality. The study was authored by Sarah S. Alghanem and last updated in May 2026.

Use Cases

• Modeling the relationship between colistin maintenance dose and clinical cure rates based on logistic regression results.
• Analyzing risk factors for nephrotoxicity associated with higher antibiotic doses mentioned in the study.
• Comparing patient outcomes between ICU and non-ICU settings based on the described cohort split.
• Investigating the safety profile of colistin by assessing reported rates of neurotoxicity and mortality.

Strengths

• Includes data from 205 patients across five hospitals, providing a multi-center perspective.
• Study outcomes are clearly defined, including clinical cure, nephrotoxicity, neurotoxicity, and mortality.
• Analysis adjusted for multiple covariates including age, sex, hospital unit, and baseline creatinine clearance.

Limitations

• Row count and column-level documentation are unknown, which limits suitability assessment.
• The dataset is very small at 32.2 KB, indicating limited scope and detail.
• Data may reflect geographic and institutional bias specific to Kuwait public hospitals.

Provenance

Source

figshare

Collection Method

Multicentre, retrospective, observational study using hospital data.

Time Range

null

Freshness

Last updated 2026-05-08 05:53:35; freshness should be verified.

Geography

Kuwait