Supplementary File 1: Combined LZH and ZJ Treatment Effects on Skin Wound Healing

A supplementary document from a study investigating the effects of Lingzhi Huang capsules and Zeng Jian Health Tonic on skin wound healing. The 18.1 MB DOCX file contains results from in vivo mouse models and in vitro HUVEC cell experiments, authored by Li Liu and last updated in June 2026. The study uses LC-MS/MS, histopathology, and protein array analysis to explore mechanisms involving BMP5 and ferroptosis.

Use Cases

• Analyze the molecular mechanisms of traditional Chinese medicine formulations based on the described protein array and network pharmacology results.
• Study the relationship between BMP5 expression and ferroptosis inhibition based on the described in vitro validation experiments.
• Compare therapeutic effects of combined versus individual treatments based on the described wound closure, collagen deposition, and angiogenesis metrics.
• Investigate pathways linking oxidative stress markers (ROS, SOD, GSH, MDA) to tissue repair based on the described HUVEC cell assays.

Strengths

• File size is 18.1 MB, indicating substantial supplementary content.
• Study design is described in detail, including in vivo mouse models and in vitro HUVEC cell experiments.
• Mechanistic validation is reported, including BMP5 overexpression and knockdown experiments.

Limitations

• The dataset is a single DOCX file; column-level data structure and row count are unknown.
• Data is presented as a supplementary document, which may require extraction and reformatting for computational analysis.
• Freshness should be verified as the last update date is in the future (2026-06-02).

Provenance

Source

figshare, authored by Li Liu.

Collection Method

Data generated from laboratory experiments including LC-MS/MS characterization, mouse wound models, HUVEC cell culture, and protein array profiling.

Freshness

Last updated 2026-06-02 05:42:35