Supplementary file 1_Comprehensive genomics, systems, and structural assessment for novel

665 PRSP genomes from Indian clinical isolates collected between 1996 and 2022 were analyzed. The dataset likely contains results from an in silico strategy integrating genomics, GWAS, network analyses, and membrane protein simulations. It was authored by Avani Panickar and last updated in April 2026.

Use Cases

• Prioritizing antimicrobial drug targets based on essentiality screening and functional annotation.
• Analyzing gene clusters associated with penicillin resistance based on GWAS results.
• Evaluating the druggability and structural stability of candidate proteins based on modeling and simulation results.
• Identifying conserved and essential targets within bacterial populations based on evolutionary conservation analysis.

Strengths

• Analysis includes 665 high-quality genome assemblies from a defined time range (1996-2022).
• The methodology integrates multiple computational approaches: genomics, GWAS, network analysis, and structural modeling.
• The dataset is licensed under CC-BY-4.0, allowing for open reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is a 2.2 MB DOCX file, suggesting it may be a supplementary document rather than raw data tables.
• Row count is unknown, which may limit suitability assessment for direct computational analysis.

Provenance

Source

figshare

Collection Method

Genomes were from Indian clinical isolates; analysis involved pangenome construction, GWAS, and computational prioritization.

Time Range

1996-2022

Freshness

Last updated 2026-04-29 05:54:29; freshness should be verified.

Geography

India