Supplementary file 1_Context-dependent interaction between oxytocin gene polymorphisms and

Zeping Xu's dataset from figshare contains clinical and genetic data from 414 Chinese Han male adults undergoing acute alcohol withdrawal. The data was collected to examine the interaction between oxytocin gene polymorphisms and alcohol dependence on anxiety and depression symptoms under different social contexts. The dataset was last updated on 2026-05-15.

Use Cases

• Analyzing correlations between alcohol dependence severity and symptoms of depression and anxiety based on self-reported measures.
• Investigating gene-environment interactions between specific oxytocin polymorphisms (rs2740210, rs2740209) and alcohol dependence on anxiety symptoms.
• Studying the moderating effect of social context (living with family, marital status) on genetic risk for anxiety during withdrawal.

Strengths

• Includes data from 414 participants, providing a substantial sample size for analysis.
• Contains multiple data types: genetic (OXT polymorphisms), clinical (depression/anxiety scores, alcohol dependence severity), and demographic (social/environmental context).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect geographic and demographic bias inherent to the sample of Chinese Han males.

Provenance

Source

Zeping Xu via figshare.

Collection Method

Blood samples for genotyping, self-reported measures of depression and anxiety, assessments of alcohol dependence severity, and demographic questionnaires.

Freshness

Last updated 2026-05-15 05:28:06; freshness should be verified.

Geography

Chinese Han male adults.