Halorubrum Lacusprofundi Proteome Analysis for Cryo-Hypersaline Adaptation

Antarctic Deep Lake provides a proteome-scale analysis of the haloarchaeon Halorubrum lacusprofundi, focusing on protein adaptation to combined cold and high-salt stress. The dataset includes physicochemical profiling of more than 3,000 proteins, with comparative analysis against mesophilic, psychrophilic, and halophilic reference organisms. Author Shubham Pandey published this work on figshare under a CC-BY-4.0 license, last updated in April 2026.

Use Cases

• Study protein physicochemical property adaptation based on described acidic enrichment and isoelectric point shifts.
• Model protein solubility and function in high ionic strength environments based on surface charge redistribution analysis.
• Compare conformational dynamics between extremophiles based on flexibility profiling mentioned in the results.
• Investigate layered adaptation strategies for polyextreme survival based on substitution analysis findings.

Strengths

• Analysis covers more than 3,000 proteins from the dominant Antarctic Deep Lake organism.
• Integrates high-confidence structural prediction with genome-wide physicochemical profiling.
• Includes comparative analysis against multiple reference organism types (mesophilic, psychrophilic, halophilic).

Limitations

• Dataset size is 55.7 KB, indicating a very limited scope, likely a supplementary document.
• Row count and column-level data are unknown, limiting suitability assessment.
• The primary file format is DOCX, which may require conversion for computational analysis.

Provenance

Source

figshare

Collection Method

Comparative proteome-scale analysis integrating structural prediction and physicochemical profiling.

Freshness

Last updated 2026-04-17 05:21:49

Geography

Antarctic Deep Lake