C. elegans Transcriptomic Response to Simulated Space Conditions and Viral Infection

Ana Villena-Giménez's dataset contains transcriptomic profiles of Caenorhabditis elegans under simulated space conditions. The data was generated via RNA-sequencing to analyze gene expression under low-shear modeled microgravity, radiologically shielded environments, and Orsay virus infection. It was last updated on 2026-03-18 and is shared under a CC-BY-4.0 license.

Use Cases

• Identify gene expression changes in oxidative stress and lipid metabolism pathways based on the described stress responses.
• Analyze the antagonistic interaction between abiotic stress and viral infection based on the described transcriptional attenuation.
• Study the modulation of immune effector and proteostasis pathways based on the gene ontology analyses mentioned.
• Investigate viral replication dynamics based on the described viral load and RNA2/RNA1 ratio data.

Strengths

• Data is based on RNA-sequencing, a standard method for transcriptomic analysis.
• The study investigates a novel combination of simulated space stressors (LSMMG and RSE) with viral infection.
• Dataset is 19.0 MB in size, indicating a focused and manageable download.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The primary data file is a DOCX format, which may require extraction of underlying data tables.

Provenance

Source

Ana Villena-Giménez

Collection Method

RNA-sequencing of C. elegans under controlled stress and infection conditions.

Freshness

Last updated 2026-03-18 06:57:14; freshness should be verified.