Cost-Effectiveness Analysis of Opioid-Sparing Strategies in Bariatric Surgery

A Markov decision analysis model compares pharmacoeconomic and clinical outcomes over a 5-year horizon for elective bariatric surgery. The model, developed by Brian A. Williams, evaluates two intrathecal morphine enhanced recovery strategies against historical controls. Results indicate a comprehensive strategy with scheduled booster non-opioids and antiemetics may reduce costs by US$500–$1,900 per case while preserving 21–35 quality-adjusted life days.

Use Cases

• Modeling long-term cost burdens of perioperative opioid use based on a 5-year time horizon.
• Comparing quality-adjusted life day outcomes between different enhanced recovery strategies.
• Conducting sensitivity analyses on pharmacoeconomic model parameters for bariatric surgery.

Strengths

• Model results are described as robust over many parameters in sensitivity analyses.
• The analysis includes a specific cost burden range of US$500–$1,900 per case.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is a 200.1 KB PDF file, suggesting limited scope and likely containing summary results rather than raw data.

Provenance

Source

figshare

Collection Method

Markov decision analysis model developed from observational research.

Time Range

5-year model horizon following a 2–4-day surgical encounter.

Freshness

Last updated 2026-05-15 05:42:42; freshness should be verified.