Porcine Decellularized Carotid Arteries for Vascular Graft Implantation

Decellularized porcine carotid arteries were assessed for use as vascular grafts. The dataset includes histology, residual DNA content (32.6 ± 5.8 ng/mg), mechanical properties, and 3-month in vivo implantation results. It was authored by Liqi Zhao and last updated on 2026-05-26.

Use Cases

• Evaluating decellularization efficacy based on residual DNA content and histology results.
• Assessing mechanical suitability for grafts based on tensile properties and burst pressure data.
• Studying host-mediated remodeling based on in vivo results showing endothelial coverage and cellular infiltration.
• Screening for hemocompatibility based on hemolysis ratio and platelet adhesion morphology.

Strengths

• Residual DNA content is quantified (32.6 ± 5.8 ng/mg) and compared to an immunogenicity threshold (50 ng/mg).
• In vivo results cover a 3-month implantation period, showing graft patency and structural integrity.
• Hemocompatibility is assessed with specific metrics, including a hemolysis ratio below 5%.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (107.0 KB), indicating limited scope.

Provenance

Source

figshare

Collection Method

Data likely originates from laboratory experiments using a detergent-enzymatic decellularization protocol on porcine carotid arteries.

Freshness

Last updated 2026-05-26 06:02:10; freshness should be verified.