DENTALE: A Validated Radiographic Scoring Tool for Pediatric Cancer Survivors

A 353.9 KB PDF describes the DENTALE tool, a validated radiographic scoring system for assessing late dental and maxillofacial adverse effects in survivors of pediatric rhabdomyosarcoma. The tool was developed and validated by Koen B. Krommenhoek, with interobserver reliability showing good to excellent agreement (ICC: 0.857–0.939). It achieved 100% sensitivity and 90.0% specificity for referral decisions in a validation cohort of 83 survivors.

Use Cases

• Standardizing research reporting on dental late effects based on the described anatomical features (condylar process, mandibular ramus, alveolar process, tooth presence, morphology).
• Supporting evidence-based referral to specialized dental care based on the tool's validated threshold score of 16 points.
• Facilitating comparisons of late effects across different childhood cancer treatment modalities using the standardized DENTALE methodology.

Strengths

• The tool demonstrated good to excellent interobserver reliability with ICCs ranging from 0.857 to 0.939.
• Validation achieved 100% sensitivity and 90.0% specificity for referral decisions using a 16-point threshold.
• Content validity was established through expert consensus, and clinical utility was evaluated with sensitivity and specificity analyses.

Limitations

• The dataset is a 353.9 KB PDF document describing the tool; the underlying patient image data or scoring tables are not included.
• Row count and column-level documentation for any potential accompanying data are unknown.
• The data reflects a specific cohort of pediatric rhabdomyosarcoma survivors, which may limit generalizability to other cancer types.

Provenance

Source

figshare, authored by Koen B. Krommenhoek.

Collection Method

Developed through orthopantomogram (OPG) assessment by dentists, following a systematic tool development and validation approach.

Freshness

Last updated 2026-05-22 06:11:10.