VELscope Diagnostic Efficacy for Oral Potentially Malignant Disorders: A Meta-Analysis

A systematic review and meta-analysis from 2026 evaluates the diagnostic efficacy of VELscope for oral potentially malignant disorders. The analysis includes 24 studies retrieved from eight databases, reporting a sensitivity of 84% and specificity of 45%. The supplementary file was authored by Yan Li and is licensed under CC-BY-4.0.

Use Cases

• Evaluating the sensitivity and specificity of VELscope based on the reported meta-analysis results
• Conducting subgroup analysis on diagnostic test accuracy based on study design and bias risk factors mentioned in the description
• Supporting systematic review methodology based on the described QUADAS-2 quality assessment and meta-regression analysis

Strengths

• Meta-analysis includes 24 studies retrieved from 8 databases, providing a broad evidence base
• Reports specific diagnostic metrics: sensitivity 84% (95% CI, 0.78–0.89) and specificity 45% (95% CI, 0.33–0.59)
• Includes subgroup analysis on factors influencing test sensitivity, such as study design and risk of bias

Limitations

• The dataset is a 819.7 KB DOCX file, which is a small supplementary document rather than a primary data table
• Row count and column-level data are unknown, limiting suitability assessment for direct computational analysis
• Column-level documentation is absent; field semantics must be inferred after download

Provenance

Source

figshare

Collection Method

Systematic search across six English and two Chinese databases, followed by meta-analysis.

Freshness

Last updated 2026-04-17 05:09:28