Supplementary file 1_Differences in cortisol levels between preterm and term infants: a sy

74 studies were included in a systematic review and meta-analysis comparing cortisol levels between preterm and term infants. The dataset, authored by Yun Li and last updated in June 2026, contains the supplementary file for this combined meta-analysis and Mendelian randomization study. The research found lower cortisol levels in preterm infants' umbilical cord blood and peripheral blood on the first day after birth.

Use Cases

• Conducting a meta-analysis on infant cortisol levels based on aggregated data from 74 studies.
• Assessing causal relationships between preterm birth and cortisone levels using Mendelian randomization methods.
• Comparing cortisol measurement outcomes based on specimen type, measurement age, and steroid hormone usage as described in the study.

Strengths

• The analysis is based on a systematic review of 74 studies, providing a substantial evidence base.
• The study protocol was registered with PROSPERO (CRD42024606328), indicating a structured methodological approach.
• Results include subgroup analyses by specimen type, measurement method, and age, offering detailed insights.

Limitations

• The primary data file is a 14.0 MB DOCX document; the underlying raw or tabular data is not directly accessible.
• Row and column-level details are unknown, requiring manual inspection of the document to understand the data structure.
• The description is specific to the study's findings but does not document the format or variables within the supplementary file itself.

Provenance

Source

figshare, authored by Yun Li.

Collection Method

Systematic review and meta-analysis of studies from 10 databases, combined with Mendelian randomization analysis.

Time Range

Studies from database inception to August 2024 were included.

Freshness

Last updated 2026-06-02 05:33:05.