Clinical Outcomes for Crohn's Disease with Severe Bleeding in Hunan Province, China

A multicenter retrospective cohort study in Hunan Province, China, analyzed three treatments for Crohn's disease complicated by acute severe lower gastrointestinal bleeding. The study, authored by Shuoyi Yao and last updated in March 2026, compares infliximab, surgical, and traditional hemostatic therapies on clinical and economic outcomes. Results indicate infliximab therapy was associated with lower rebleeding risk and hospital costs compared to surgery.

Use Cases

• Compare rebleeding risk between treatment groups based on multivariate COX regression hazard ratios
• Analyze anti-inflammatory effects based on C-reactive protein and erythrocyte sedimentation rate conversion rates
• Evaluate economic benefits based on duration and cost of hospital stay metrics
• Assess complication incidence across different therapeutic interventions

Strengths

• Multicenter retrospective cohort design provides comparative clinical data
• Analysis includes both clinical outcomes (e.g., hemostasis, inflammation) and economic metrics (cost, duration)
• Results include statistically significant findings with p-values and confidence intervals

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Data may reflect geographic bias inherent to the Hunan Province, China study population

Provenance

Source

figshare

Collection Method

Multicenter retrospective cohort study

Time Range

null

Freshness

Last updated 2026-03 17 13:05:51; freshness should be verified

Geography

Hunan Province, China