Skin Microbiome Profiles from Pediatric Atopic Dermatitis Patients and Healthy Controls

Shotgun metagenomic sequencing data from skin samples collected from 12 pediatric atopic dermatitis patients and 12 healthy controls. The dataset includes analyses of microbial diversity, taxonomic composition, and functional profiles. It was authored by Zirui Feng and last updated on April 29, 2026.

Use Cases

• Compare microbial diversity indices (Shannon, Chao1) between disease severity groups.
• Analyze taxonomic abundance profiles, particularly for Staphylococcus and Streptococcus genera.
• Investigate functional alterations in microbial activity using KEGG and Gene Ontology annotations.
• Assess virulence factors and pathogen-host interactions (PHI) in the context of barrier dysfunction.

Strengths

• Includes data from a controlled prospective study with 12 patients and 12 healthy controls.
• Provides functional analysis beyond taxonomy, including KEGG, GO, virulence factors, and PHI.
• Analyzes samples from different skin regions and across disease severity levels.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is 4.0 MB, suggesting a relatively small scale.

Provenance

Source

figshare

Collection Method

Skin samples were collected and genomic DNA underwent shotgun metagenomic sequencing.

Freshness

Last updated 2026-04-29 05:52:32; freshness should be verified.