Systematic Review on Liposomal Bupivacaine in Autologous Breast Reconstruction

A 17.1 KB document summarizing a systematic review of 10 studies on liposomal bupivacaine for pain management in autologous breast reconstruction. The review, authored by Waiel A. Daghistani and published on figshare in 2026, synthesizes evidence on opioid consumption, hospital stay, and other recovery outcomes. Results show heterogeneous effects, with some studies reporting significant reductions in opioid use and others showing no difference.

Use Cases

• Comparing analgesic efficacy based on reported opioid consumption metrics
• Evaluating patient recovery timelines based on length of hospital stay and time to ambulation
• Assessing safety profiles based on reported adverse event rates like seroma formation

Strengths

• Includes specific quantitative results, such as opioid consumption comparisons (e.g., 512 vs. 395 mg) and p-values
• Follows PRISMA guidelines for systematic review methodology
• Analyzes 10 studies with sample sizes ranging from 16 to 1,017 patients

Limitations

• The dataset is a 17.1 KB DOCX file, indicating a limited scope primarily containing review text
• Row count and column-level data are unknown, limiting direct computational analysis
• The description notes heterogeneity in study designs and outcome reporting, complicating synthesis

Provenance

Source

figshare

Collection Method

Systematic literature review of PubMed, Cochrane CENTRAL, Web of Science, and Scopus up to February 2025.

Freshness

Last updated 2026-05-07.