Overview of Systematic Reviews on Noninvasive Brain Stimulation for Poststroke Depression
by Shi Liu·Updated 2mo ago
21.4 KB1files
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Description
20 meta-analyses and systematic reviews assess the effectiveness and safety of noninvasive brain stimulation for poststroke depression. The overview evaluates reporting quality, methodological quality, and evidence quality using PRISMA, AMSTAR-2, and GRADE tools. It includes analysis of primary outcome indicators for depressive symptoms and secondary indicators for neurological function, cognitive function, and adverse reactions.
Use Cases
Analyze the distribution of evidence quality levels among the 66 GRADE-assessed outcome indicators to identify research gaps.
Compare the methodological quality ratings from AMSTAR-2 across the 20 included reviews to understand common weaknesses.
Synthesize findings on the primary outcome indicator of depressive symptoms from multiple systematic reviews.
Evaluate the safety profile of NIBS treatments by reviewing extracted data on the secondary outcome indicator of adverse reactions.
Strengths
Provides a structured evaluation of 20 existing meta-analyses and systematic reviews.
Applies three established quality assessment frameworks: PRISMA, AMSTAR-2, and GRADE across 66 evidence bodies.
Focuses on a clinically relevant topic, analyzing both effectiveness and safety outcome indicators for poststroke depression treatment.
Limitations
The underlying systematic reviews are of generally low quality, with 60% rated critically low by AMSTAR-2 and 63.6% of evidence rated very low by GRADE.
The dataset is a single 21.4 KB document, offering a textual overview rather than raw, analyzable tabular data.
No primary patient-level data is included; conclusions are based on the synthesis of previously published reviews.
Provenance
Source
Author Shi Liu, published on figshare.
Collection Method
Comprehensive search of multiple databases including PubMed, EMBASE, Cochrane Library, Web of Science, CNKI, VIP, Wan Fang, and CBM for systematic reviews and meta-analyses.
Freshness
Last updated March 2026.
Data is contained within a single DOCX file; extraction of structured information would require manual review or text parsing. Licensed under CC BY 4.0.