Meta-Analysis of Gynostemma Pentaphyllum Efficacy for Glycemic Control

Eight clinical studies involving 584 patients form the basis of this meta-analysis on a traditional herb. The study, authored by Ruoshi Wang and last updated in April 2026, reports pooled mean differences for fasting plasma glucose, HbA1c, and postprandial glucose. It also includes a systematic review of the herb's proposed antidiabetic mechanisms of action.

Use Cases

• Validate the clinical efficacy of Gynostemma pentaphyllum based on pooled results from eight studies
• Analyze the relationship between treatment duration and glycemic outcomes based on the finding that long-term treatments showed superior efficacy
• Investigate multi-target pharmacological mechanisms for diabetes based on the review of pathways like glucose uptake and insulin secretion
• Compare the effectiveness of monotherapy versus combination therapy for glycemic control based on the study's results

Strengths

• Includes specific pooled effect sizes (e.g., HbA1c MD = -1.01%) with 95% confidence intervals
• Based on a systematic search of three major databases (PubMed, CNKI, Embase)
• Covers multiple glycemic markers: FPG, 2hPG, and HbA1c
• Released under a permissive CC-BY-4.0 license

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The 2.2 MB file size suggests the document is the primary content, not a large underlying dataset

Provenance

Source

figshare, authored by Ruoshi Wang

Collection Method

Meta-analysis and systematic review of clinical studies from PubMed, CNKI, and Embase

Time Range

Temporal coverage of the included clinical studies is not specified

Freshness

Last updated 2026-04 15 08:09:22

Geography

Spatial coverage is not specified, but the herb is widely consumed in Asia